RT Journal Article SR Electronic T1 Exercise for cognitive brain health in aging JF Neurology: Clinical Practice FD Lippincott Williams & Wilkins SP 257 OP 265 DO 10.1212/CPJ.0000000000000460 VO 8 IS 3 A1 Joyce Gomes-Osman A1 Danylo F. Cabral A1 Timothy P. Morris A1 Katalina McInerney A1 Lawrence P. Cahalin A1 Tatjana Rundek A1 Augusto Oliveira A1 Alvaro Pascual-Leone YR 2018 UL http://cp.neurology.org/content/8/3/257.abstract AB Purpose of review We systematically appraised randomized controlled trials proposing exercise to influence cognition in older adults to (1) assess the methodologic quality using Cochrane criteria; (2) describe various exercise dose measures and assess their relationship with improved cognitive performance; and (3) identify consistent patterns of reported effects on cognition.Recent findings There was overall good methodologic quality in all 98 included studies. The assessment of the relationship between improved cognition and various measures of exercise dose (session duration, weekly minutes, frequency, total weeks, and total hours) revealed a significant correlation with total hours. Improvements in global cognition, processing speed/attention, and executive function were most stable and consistent.Summary We found that exercising for at least 52 hours is associated with improved cognitive performance in older adults with and without cognitive impairment. Exercise modes supported by evidence are aerobic, resistance (strength) training, mind–body exercises, or combinations of these interventions.