PT - JOURNAL ARTICLE AU - Mickaela Roy AU - Stephane Welschbillig AU - Marie Cantier AU - Dorian Chauvet AU - Pierre Bourdillon AU - Nicolas Engrand TI - Rescue Epidural Saline Patch for Comatose Patients With Refractory Convexity Spontaneous Subacute Subdural Hematoma AID - 10.1212/CPJ.0000000000200137 DP - 2023 Apr 01 TA - Neurology: Clinical Practice PG - e200137 VI - 13 IP - 2 4099 - http://cp.neurology.org/content/13/2/e200137.short 4100 - http://cp.neurology.org/content/13/2/e200137.full AB - Objectives Convexity spontaneous subacute subdural hematoma (CSSSH) frequently relapse after one or more surgical drainages. This may be due to spontaneous intracranial hypotension (SIH), for which the gold standard treatment is the epidural blood patch. In this study, we report 4 cases of refractory CSSSH treated with rescue epidural saline patch, although history and imaging studies showed no evidence of SIH.Methods All 4 patients received a lumbar saline epidural rescue patch for consciousness impairment associated with refractory CSSSH, and one is particularly detailed. No patient had typical radiologic signs of SIH or, on the contrary, uncal herniation that could have indicated intracranial hypertension.Results The Glasgow Coma Scale score improved significantly in the days after application of the epidural patch in 3 patients. All patients showed an improvement of the CT scan. Two patients underwent lumbar pressure measurement to confirm low values before the epidural injection, and for one, the intrathecal pressure profile during epidural patching is presented.Discussion An epidural patch may be considered in managing CSSSH with no uncal herniation, even in the absence of signs of SIH on brain and spinal imaging. Whether it should be combined with surgical evacuation or used as first-line therapy remains to be determined.