RT Journal Article
SR Electronic
T1 Carotid Intimal Sarcoma Presenting as Large Vessel Occlusion and Diagnosed by Embolus Histopathology
JF Neurology: Clinical Practice
FD Lippincott Williams & Wilkins
SP e200129
DO 10.1212/CPJ.0000000000200129
VO 13
IS 1
A1 Mahlon D. Johnson
A1 Eli J. Rogers
A1 Muhammad Waqas Khan
A1 Phillip D. McMullen
A1 Sajal Medha K Akkipeddi
A1 Thomas Mattingly
A1 Curtis G. Benesch
A1 Matthew T. Bender
YR 2023
UL http://cp.neurology.org/content/13/1/e200129.abstract
AB Objective The objective of this study was to present the clinical, histopathologic, and radiographic findings of a unique case of intimal sarcoma (IS) embolus presenting as a large vessel occlusion causing an ischemic stroke without a detectable primary tumor site.Methods Extensive examinations, multimodal imaging, laboratory testing, and histopathologic analysis were used in evaluation.Results We report the case of a patient who presented with acute embolic ischemic stroke and was found to have IS based on a histopathologic evaluation of his embolectomy specimen. Subsequent comprehensive imaging studies failed to detect a primary tumor site. Multidisciplinary interventions including a course of radiotherapy were performed. The patient died of recurrent multifocal strokes 92 days after diagnosis.Discussion Meticulous histopathologic analysis should be conducted on cerebral embolectomy specimens. Histopathology may be useful in diagnosing IS.