PT  - JOURNAL ARTICLE
AU  - Nadine Emanuela Stähli
AU  - Sandra Bigi
AU  - Sebastian Grunt
AU  - Karen Lidzba
AU  - Martina Studer
TI  - Systematic review of accelerated long-term forgetting in children and adolescents with neuropediatric diseases
AID  - 10.1212/CPJ.0000000000200081
DP  - 2022 Oct 12
TA  - Neurology: Clinical Practice
PG  - 10.1212/CPJ.0000000000200081
4099  - http://cp.neurology.org/content/early/2022/10/12/CPJ.0000000000200081.short
4100  - http://cp.neurology.org/content/early/2022/10/12/CPJ.0000000000200081.full
AB  - Purpose of review: Accelerated long-term forgetting (ALF) describes the phenomenon of normal learning and memory performance after short delays, but greater forgetting after longer delays which is not objectified in standardized memory tests. The topic is attracting increasing interest due to its clinical importance. Studies investigating pediatric ALF remain rare and no systematic review exists.Recent findings: Based on our systematic literature search, twelve studies were found. Although most studies investigated ALF in children with epilepsy (n = 9), there is also evidence of ALF in children after traumatic brain injury (n = 1) and 22q11.2 deletion syndrome (n = 1).Summary: To date, only a dozen of studies have investigated pediatric ALF. There is evidence that ALF is not an epilepsy-specific disorder, replicating findings of studies with adult patients. As ALF is missed using standardized assessments, we propose to add delayed time-points of testing memory performance.