PT - JOURNAL ARTICLE AU - Mula, Marco AU - Kanner, Andres M. AU - Jetté, Nathalie AU - Sander, Josemir W. TI - Psychiatric Comorbidities in People With Epilepsy AID - 10.1212/CPJ.0000000000000874 DP - 2021 Apr 01 TA - Neurology: Clinical Practice PG - e112--e120 VI - 11 IP - 2 4099 - http://cp.neurology.org/content/11/2/e112.short 4100 - http://cp.neurology.org/content/11/2/e112.full AB - Purpose of Review To review the latest evidence concerning the epidemiology, clinical implications, and management of psychiatric disorders in epilepsy.Recent Findings People with epilepsy have a 2–5 times increased risk of developing any psychiatric disorder, and 1 in 3 patients with epilepsy have a lifetime psychiatric diagnosis. Psychiatric comorbidities represent a poor prognostic marker as they have been associated with a poor response to treatment (drugs and surgery), increased morbidity, and mortality. Validated screening instruments are available for mood and anxiety disorders in adults as well as attention-deficit hyperactivity disorder in children with epilepsy.Summary All patients with epilepsy should be routinely screened for psychiatric disorder at the onset and at least once a year. Patients with epilepsy and their relatives should be informed of the risk of mental health problems and the implications.