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Neurology Clinical Practice
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LETTER RE: The application of optical coherence tomography in neurologic diseases

  • Khichar Shubhakaran, MD, Dr. S. N. Medical College, Jodhpur, Indiadrkhicharsk@gmail.com
Submitted December 18, 2015

I read with interest the review on optic coherence tomography (OCT) in various neurologic diseases by Maldonado et al.1 OCT is used extensively for clinical decision-making and monitoring of many posterior segment diseases based on macular, optic nerve and retinal nerve fiber layer (RNFL) imaging.2 It is a non-invasive imaging technique and provides high-resolution, cross-sectional images of the retina, the RNFL, and the optic nerve head.2

I would like to draw particular attention to another important role OCT can play.3 OCT can aid with diagnosis, exclusion of diagnosis, and precipitation of angle closure glaucoma with topiramate use.4 Topiramate is used frequently in various neuropsychiatric conditions and is proving to be a promising drug (relatively cheap and with a low side effect profile). With better definition of optic nerve pathology, OCT will prove a useful tool to monitor and avoid topiramate side effects.4

Disclosures: The author reports no disclosures.

References:

1. Maldonado RS, Mettu P, El-Dairi M, Bhatti MT.The application of optical coherence tomography in neurologic diseases. Neurol Clin Pract October 2015;5:460-469.

2. Adhi M. Optical Coherence Tomography: Current and Future Applications. Curr Opin Ophthalmol 2013;24:213-221.

3. Mitra A, Ramakrishnan R, Kader MA. Anterior segment optical coherence tomography documentation of a case of topiramate induced acute angle closure. Indian J Ophthalmol 2014;62:619-622.

4. Shubhakaran K P. Anterior segment optical coherence tomography in angle closure glaucoma with topiramate use. Indian J Ophthalmol 2014;62:1174-1175.

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Neurology: Clinical Practice: 12 (3)

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Neurology: Clinical Practice |  Print ISSN: 2163-0402
Online ISSN: 2163-0933

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