Cerebral Venous Sinus Thrombosis With Severe Thrombocytopenia: A Fatal Adverse Event Following Johnson & Johnson COVID-19 Vaccination
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Abstract
Approximately 7.98 million doses of the Johnson and Johnson adenovirus vector SARS-CoV-2 vaccine (J&J vaccine) have been administered since EUA authorization by the FDA on February 27, 20211, 2. On April 13th, the CDC/FDA recommended a pause in administration after 6 cases of cerebral venous sinus thrombosis (CVST) with thrombocytopenia were identified through the vaccine adverse event reporting system in women aged 18-48. To date, 15 cases of thrombosis with thrombocytopenia syndrome (TTS) have been reported following vaccination with J&J, with three reported fatalities2. Here we report one of those fatalities in a 35-year-old woman who developed CVST with thrombocytopenia following vaccination with the J&J vaccine.
- Received April 29, 2021.
- Accepted August 19, 2021.
- © 2021 American Academy of Neurology
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