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December 03, 2020Case

Idiopathic intracranial hypertension without intracranial hypertension

View ORCID ProfileMattia Sansone, Michelangelo De Angelis, Leonilda Bilo, Vincenzo Bonavita, View ORCID ProfileRoberto De Simone
First published December 3, 2020, DOI: https://doi.org/10.1212/CPJ.0000000000001022
Mattia Sansone
1 Department of Neuroscience, Reproductive Sciences and Odontostomatology, Headache Centre, University Federico II of Naples, Via Pansini, 5, 80131 Naples, Italy
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Michelangelo De Angelis
2 Department of Neurosurgery, IRCCS “Neuromed”, Pozzilli (IS), Italy
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Leonilda Bilo
1 Department of Neuroscience, Reproductive Sciences and Odontostomatology, Headache Centre, University Federico II of Naples, Via Pansini, 5, 80131 Naples, Italy
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Vincenzo Bonavita
3 Istituto di Diagnosi e Cura Hermitage Capodimonte, Naples, Italy
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Roberto De Simone
1 Department of Neuroscience, Reproductive Sciences and Odontostomatology, Headache Centre, University Federico II of Naples, Via Pansini, 5, 80131 Naples, Italy
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Citation
Idiopathic intracranial hypertension without intracranial hypertension
Mattia Sansone, Michelangelo De Angelis, Leonilda Bilo, Vincenzo Bonavita, Roberto De Simone
Neurol Clin Pract Dec 2020, 10.1212/CPJ.0000000000001022; DOI: 10.1212/CPJ.0000000000001022

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Abstract

The intracranial pressure (ICP) show large daily fluctuation, mainly due to postural changes and physical activity (e.g. it goes up to 470 mmH2O under Valsalva manoeuvre1). Consequently, the dural sinus must be sufficiently rigid in order to avoid its collapse during cerebrospinal fluid (CSF) pressure peaks. Hereby, we describe a patient with collapsible dural sinus associated with an intracranial hypertension syndrome without a detectable raised ICP, suggesting that a number of crucial assumptions on idiopathic intracranial hypertension with (IIH) or without papilledema (IIHWOP) might be discussed.

  • Received June 10, 2020.
  • Accepted September 22, 2020.
  • © 2020 American Academy of Neurology

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