We thank Dr. Sethi for his interest in our article1 and thoughtful comments. We agree that a one-size-fits-all approach to antiepileptic drug (AED) discontinuation would not make sense; as we stated in the Introduction, ultimately this remains an individualized decision. Nevertheless, there are several clinical scenarios that may potentially represent a rather homogeneous population of patients, for example those with juvenile myoclonic epilepsy or those who underwent a successful uncomplicated temporal lobectomy (with all the caveats related to driving status and access to care that were eloquently detailed by Dr. Sethi), who could be studied with an appropriate model for prediction of seizure recurrence after AED discontinuation at different time points. This model could potentially represent a useful clinical tool to be utilized in conjunction with several other clinical, personal, and socioeconomic factors when making an individualized decision about AED withdrawal.
Footnotes
Author disclosures are available upon request (ncpjournal{at}neurology.org).
- © 2018 American Academy of Neurology
References
- 1.↵
The Nerve!: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Cutaneous α-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease
Dr. Rizwan S. Akhtar and Dr. Sarah Brooker
► Watch
Alert Me
Recommended articles
Uncertainties from a worldwide survey on antiepileptic drug withdrawal after seizure remission
Practice Current: When do you stop antiepileptic drugs in patients with genetic generalized epilepsies and in those with focal epilepsies?
Discontinuation of antiepileptic drugs after successful epilepsy surgery
Prognosis of juvenile myoclonic epilepsy 45 years after onset