Practice Current: When do you order ancillary tests to determine brain death?
Citation Manager Formats
Make Comment
See Comments

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Abstract
Brain death has been accepted as a legal definition of death in most countries, but practices for determining brain death vary widely. One source of variation is in the use of ancillary tests to assist in the diagnosis of brain death. Through case-based discussions with 3 experts from 3 continents, this article discusses selected aspects of brain death, with a focus on the use of ancillary tests. In particular, we explore the following questions: Are ancillary tests necessary, or is the clinical examination sufficient? What ancillary tests are preferred, and under which circumstances? Are ancillary tests required when the primary mechanism of injury is brainstem injury? Should the family's wishes play a role in the need for ancillary tests? The same case-based questions were posed to the rest of our readership in an online survey, the preliminary results of which are also presented.
Footnotes
Funding information and disclosures are provided at the end of the article. Full disclosure form information provided by the authors is available with the full text of this article at Neurology.org/cp.
Explore this topic: NPub.org/NCP/pc07
Interactive world map: NPub.org/NCP/map07
More Practice Current: NPub.org/NCP/practicecurrent
- Received February 7, 2018.
- Accepted April 11, 2018.
- © 2018 American Academy of Neurology
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)
Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here
Purchase
Individual access to articles is available through the Add to Cart option on the article page. Access for 1 day (from the computer you are currently using) is US$ 39.00. Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means. The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use. Distributing copies (electronic or otherwise) of the article is not allowed.
The Nerve!: Rapid online correspondence
- Author Response: Practice Current: When do you order ancillary tests to determine brain death?
- Nathaniel M. Robbins, Assistant Professor of Neurology, Dartmouth Geisel School of Medicine
- James L. Bernat, Emeritus Professor of Neurology (Active), Dartmouth Geisel School of Medicine
Submitted July 06, 2018 - Reader Response: Ancillary tests in brain death confirmation
- Calixto Machado, Department of Clinical Neurophysiology, Institute of Neurology and Neurosurgery, Havana, Cuba
- Mario Estévez, Department of Clinical Neurophysiology, Institute of Neurology and Neurosurgery, Havana, Cuba
Submitted June 12, 2018
REQUIREMENTS
If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
- Article
- Abstract
- A brief history of brain death
- Brain death determination
- The use of ancillary testing in the determination of brain death
- Controversies in brain death diagnosis: Brainstem death or whole brain death and ancillary tests of cortical function
- Expert opinion
- Author contributions
- Study funding
- Disclosure
- Footnotes
- References
- Figures & Data
- Info & Disclosures
Use of Whole-Genome Sequencing for Mitochondrial Disease Diagnosis
Dr. Robert Pitceathly and Dr. William Macken
► Watch
Related Articles
- No related articles found.
Topics Discussed
Alert Me
Recommended articles
-
Article
Variability in reported physician practices for brain death determinationSherri A. Braksick, Christopher P. Robinson, Gary S. Gronseth et al.Neurology, January 25, 2019 -
Special Article
Evidence-based guideline update: Determining brain death in adultsReport of the Quality Standards Subcommittee of the American Academy of NeurologyEelco F.M. Wijdicks, Panayiotis N. Varelas, Gary S. Gronseth et al.Neurology, June 07, 2010 -
Contemporary Issues
An interdisciplinary response to contemporary concerns about brain death determinationAriane Lewis, James L. Bernat, Sandralee Blosser et al.Neurology, January 31, 2018 -
Article
Practice variability in brain death determinationA call to actionClaire N. Shappell, Jeffrey I. Frank, Khalil Husari et al.Neurology, November 06, 2013