Rabies encephalitis presenting with new-onset refractory status epilepticus (NORSE)
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A 15-year-old girl, previously healthy with normal developmental history, had an episode of unilateral arm jerking at school followed by transient loss of consciousness. Two weeks later, she presented to the emergency department with recurrent generalized convulsions despite treatment with lorazepam and fosphenytoin. In retrospect, her family reported a 1-month history of personality changes (i.e., listlessness) and decline in academic performance. There was no family history of epilepsy, metabolic disorders, or immunodeficiency. The patient resided in rural northeastern Kentucky. There was no recent travel history.
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Funding information and disclosures are provided at the end of the article. Full disclosure form information provided by the authors is available with the full text of this article at Neurology.org/cp.
- Received December 19, 2016.
- Accepted April 17, 2017.
- © 2017 American Academy of Neurology
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The Nerve!: Rapid online correspondence
- Author Response: Rabies encephalitis presenting with new-onset refractory status epilepticus (NORSE)
- Jonathan H. Smith, Neurologist, Mayo Clinic, Phoenix, AZ
- Gerard J. Nuovo, Neurologist, Ohio State University, Columbus, OH
- Mauricio Villamar, Neurologist, Brigham and Women's Hospital, Boston, MA
Submitted September 05, 2018 - Reader Response: Rabies encephalitis presenting with new-onset refractory status epilepticus (NORSE)
- Alan C. Jackson, Departments of Internal Medicine (Neurology) and of Medical Microbiology, University of Manitoba
- Marc R. Del Bigio, Department of Pathology, University of Manitoba
Submitted May 23, 2018
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