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Avitene, generically termed microfibrillar collagen, is a surgical hemostatic agent. Collagen-based hemostats are widely used to trigger platelet aggregation and reinforce the fibrin clot. Rarely, Avitene has been reported to induce a granulomatous reaction in the CNS, usually as a mass-forming lesion known as a textiloma. We report a case of Avitene-induced granulomatous inflammation presenting as meningitis after neurosurgery for WHO grade II atypical meningioma.
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Funding information and disclosures are provided at the end of the article. Full disclosure form information provided by the authors is available with the full text of this article at Neurology.org/cp.
- Received July 6, 2016.
- Accepted August 16, 2016.
- © 2016 American Academy of Neurology
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