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February 2017; 7 (1) Research

Hemorrhagic primary CNS angiitis and vasoconstrictive drug exposure

Mehmet A. Topcuoglu, Ruchira M. Jha, Jacob George, Matthew P. Frosch, Aneesh B. Singhal
First published November 4, 2016, DOI: https://doi.org/10.1212/CPJ.0000000000000324
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Article Information

vol. 7 no. 1 26-34
DOI: 
https://doi.org/10.1212/CPJ.0000000000000324
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
2163-0402
Online ISSN: 
2163-0933
History: 
  • Received June 16, 2016
  • Accepted August 19, 2016
  • First Published November 4, 2016.

Article Versions

Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Mehmet A. Topcuoglu, MD,
    2. Ruchira M. Jha, MD,
    3. Jacob George, MBBS,
    4. Matthew P. Frosch, MD, PhD and
    5. Aneesh B. Singhal, MD
  1. Mehmet A. Topcuoglu, MD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Ruchira M. Jha, MD,
    3. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. 1) NIH Training Grant: T-32HL007820 (Trainee, 2014-2015) 2) NIH Career Development Award: KL2 TR000146 (2015-2016) 3) NIH Career Development Award: KL2 TR001856 (2016-current)

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Jacob George, MBBS,
    4. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. Matthew P. Frosch, MD, PhD and
    5. Scientific Advisory Boards:

    1. External scientific advisory board of the NIA-funded Alzheimer Disease Center of Northwestern University School of Medicine; Ad hoc member, External scientific advisory board of the NIA-funded Alzheimer Disease Center of Mayo Clinic; Ad hoc member, external scientific advisory board to Department of Neurology, Duke University regarding establishment of an Alzheimer Disease Center

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Journal of Neuropathology and Experimental Neurology, Member of Editorial Board, 2009- Acta Neuropathologica, Member of Editorial Board, 2010- American Journal of Pathology, Member of Editorial Board, 2001-; Associate Editor, 2013-2015 FASEB Journal, Member of Editorial Board, 2010- Executive Editor, Neuropathology and Applied Neurobiology, 2015-

    Patents:

    1. NONE

    Publishing Royalties:

    1. Non-neoplastic disease of the Central Nervous System (Atlas of nontumor pathology, volume 8, ARP Press, 2009

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH, P50 AG005134, Core Director, 1984 to 3/1/2019

    Research Support, Academic Entities:

    1. Internal award from Harvard NeuroDiscovery Center

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  5. Aneesh B. Singhal, MD
    6. Scientific Advisory Boards:

    1. 1. Biogen, ACTION Stroke Trial Scientific Advisory Board Member. 2. NIH, DSMB Chair, The FEASt Trial; Fostering Eating After Stroke with tDCS (R01DC012584, Sandeep Kumar, PI)

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. (1) Sun Pharmaceuticals, Inc, travel reimbursement and honoraria

    Editorial Boards:

    1. (1) Assistant Editor, Medical Gas Research

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. (1) Biogen: my wife is an employee of Biogen

    Consultancies:

    1. (1) Biogen (2) Doch Technologies

    Speakers' Bureaus:

    1. NONE

    Other activities:

    1. (1) Event Adjudicator, Thrombolysis in Myocardial Infarction (TIMI) Trial Group.

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Boehringer Ingelheim: I am site PI for the RESPECT-ESUS stroke prevention trial

    Research Support, Government Entities:

    1. NIH-NINDS grants R01NS051412 (PI), R21NS077442 (PI), R01NS059775 (co-I), P50NS044148 (site PI), and U10NS0867290 (Deputy PI)

    Research Support, Academic Entities:

    1. (1) American Academy of Neurology (2) UptoDate. (3) Medlink Inc. Stock/Stock Options, Medical Equipment & Materials: My wife holds employee stock and stock options in Biogen

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. My wife holds employee stock and stock options in Biogen

    Legal Proceedings:

    1. I have served as a medicolegal expert witness for individual cases concerning stroke.

  1. Massachusetts General Hospital and Harvard Medical School (MAT, MPF, ABS), Boston; Neurology Department (MAT), Hacettepe University Hospitals, Ankara, Turkey; Safar Center for Resuscitation (RMJ), University of Pittsburgh Medical Center, PA; and Government Medical College (JG), Kottayam, India.
  1. Correspondence to:
    asinghal{at}partners.org
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