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April 2023; 13 (2) Editorial

Contextualizing Adverse Childhood Experiences in Patients With Parkinson Disease

The Beginnings of a Complicated Area of Neurologic Research

Adys Mendizabal
First published March 22, 2023, DOI: https://doi.org/10.1212/CPJ.0000000000200158
Adys Mendizabal
Department of Neurology (AM), University of California Los Angeles (UCLA); Institute of Society and Genetics (AM), University of California Los Angeles (UCLA); and Undergraduate Neuroscience Interdepartmental Program (uNSIDP) (AM), University of California Los Angeles (UCLA).
MD, MS
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Contextualizing Adverse Childhood Experiences in Patients With Parkinson Disease
The Beginnings of a Complicated Area of Neurologic Research
Adys Mendizabal
Neurol Clin Pract Apr 2023, 13 (2) e200158; DOI: 10.1212/CPJ.0000000000200158

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Adverse childhood experiences (ACEs) are traumatic events associated with negative health behaviors and outcomes in adulthood. The pivotal studies identifying the relationship between childhood adversity and health outcomes were conducted in the late 90s and found that having high ACEs (defined as 4 or more forms of childhood adversity) was associated with an increased risk of cardiovascular disease, lung disease, and mental health disorders, along with others.1 Having 6 or more ACEs was associated with a shortened lifespan, which was more concerning.2

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  • Funding information and disclosures are provided at the end of the article. Full disclosure form information provided by the authors is available with the full text of this article at Neurology.org/cp.

  • See page e200124

  • Received February 17, 2023.
  • Accepted February 24, 2023.
  • © 2023 American Academy of Neurology
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