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April 2023; 13 (2) Research Article

Childhood Trauma and Parkinson Disease

Associations of Adverse Childhood Experiences, Disease Severity, and Quality of Life

Indu Subramanian, Bradley McDaniels, Joshua Farahnik, Laurie K. Mischley
First published February 20, 2023, DOI: https://doi.org/10.1212/CPJ.0000000000200124
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Article Information

vol. 13 no. 2 e200124
DOI: 
https://doi.org/10.1212/CPJ.0000000000200124
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
2163-0402
Online ISSN: 
2163-0933
History: 
  • Received February 5, 2022
  • Accepted November 4, 2022
  • First Published February 20, 2023.
Copyright & Usage: 
© 2023 American Academy of Neurology

Author Disclosures

    1. Indu Subramanian, MD,
    2. Bradley McDaniels, PhD,
    3. Joshua Farahnik, ND and
    4. Laurie K. Mischley, ND, PhD, MPH
  1. Indu Subramanian, MD,
    2. Scientific Advisory Boards:

    1. None

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. Acorda- honorariumAcadia- honorarium

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. acordaAcadia

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. None

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Bradley McDaniels, PhD,
    3. Scientific Advisory Boards:

    1. None

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. Speaking honoraria, Neurochallenge Foundation for Parkinson's, 2021; Speaking honoraria, PMD Alliance, 2022.

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. None

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Joshua Farahnik, ND and
    4. Scientific Advisory Boards:

    1. None

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. None

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. None

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. Laurie K. Mischley, ND, PhD, MPH
    5. Scientific Advisory Boards:

    1. None

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. 1) PWR! Gym, speaker honoraria ($2000) June 20222) Northwestern University, speaker honoraria ($1000) Oct 2022

    Editorial Boards:

    1. NONE

    Patents:

    1. Method of using human excrement and secretions for early detection of parkinson's diseaseProvided herein are methods for early detection of Parkinson's diseases (PD), especially in individuals showing no motor symptoms, by detecting PD-distinct scent using a trained animal (such as a canine). Specific rigorous animal training in scent identification through both patient contact and training samples are also disclosed.

    Publishing Royalties:

    1. 1) Natural Therapies for Parkinson's disease, Coffeetown Press, 2009. Approx $1800/ yr

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. Copyright of the Patient-Reported Outcomes in Parkinson's Disease (PRO-PD) rating scale.The scale is freely available and I have not made any financial profit from it.

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. 1) Michael J Fox Foundation, Grant for Mitochondrial Function in Parkinson's disease

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. David Geffen School of Medicine (IS), UCLA, Department of Neurology, Los Angeles, CA; SW PADRECC (IS), West Los Angeles, Veterans Administration, CA; Department of Rehabilitation and Health Services (BM), University of North Texas, Denton; Bastyr University Research Institute (JF, LKM); and Department of Radiology (LKM), University of Washington.
  1. Correspondence
    Dr. Subramanian isubramanian{at}mednet.ucla.edu
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