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In this issue of Neurology® Clinical Practice, Qureshi et al.1 present a case of a transgender man of childbearing age with a reported body mass index of 37 who presents with idiopathic intracranial hypertension (IIH). The authors conclude that exogenous testosterone as part of a gender-affirming hormone regimen may be a potential mechanism for his diagnosis of IIH, based on prior evidence that disorders in androgen metabolism may influence CSF production.2 The authors additionally report multiple similar case reports in the literature of transmasculine patients with IIH.
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