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February 2022; 12 (1) Review

Perioperative Neurocognitive Screening Tools for At-Risk Surgical Patients

Lilia Kaustov, Andrew Fleet, Connor T.A. Brenna, View ORCID ProfileBeverley A. Orser, View ORCID ProfileStephen Choi
First published August 9, 2021, DOI: https://doi.org/10.1212/CPJ.0000000000001132
Lilia Kaustov
Department of Anesthesia (LK, AF, BAO, SC), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Perioperative Brain Health Centre (LK, CTAB, BAO, SC), Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine (CTAB, BAO, SC), University of Toronto, Ontario, Canada; and Department of Physiology (BAO), University of Toronto, Ontario, Canada.
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Andrew Fleet
Department of Anesthesia (LK, AF, BAO, SC), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Perioperative Brain Health Centre (LK, CTAB, BAO, SC), Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine (CTAB, BAO, SC), University of Toronto, Ontario, Canada; and Department of Physiology (BAO), University of Toronto, Ontario, Canada.
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  • For correspondence: andrew.fleet@sunnybrook.ca
Connor T.A. Brenna
Department of Anesthesia (LK, AF, BAO, SC), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Perioperative Brain Health Centre (LK, CTAB, BAO, SC), Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine (CTAB, BAO, SC), University of Toronto, Ontario, Canada; and Department of Physiology (BAO), University of Toronto, Ontario, Canada.
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  • For correspondence: connor.brenna@mail.utoronto.ca
Beverley A. Orser
Department of Anesthesia (LK, AF, BAO, SC), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Perioperative Brain Health Centre (LK, CTAB, BAO, SC), Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine (CTAB, BAO, SC), University of Toronto, Ontario, Canada; and Department of Physiology (BAO), University of Toronto, Ontario, Canada.
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  • ORCID record for Beverley A. Orser
  • For correspondence: beverley.orser@utoronto.ca
Stephen Choi
Department of Anesthesia (LK, AF, BAO, SC), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Perioperative Brain Health Centre (LK, CTAB, BAO, SC), Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine (CTAB, BAO, SC), University of Toronto, Ontario, Canada; and Department of Physiology (BAO), University of Toronto, Ontario, Canada.
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  • ORCID record for Stephen Choi
Full PDF
Citation
Perioperative Neurocognitive Screening Tools for At-Risk Surgical Patients
Lilia Kaustov, Andrew Fleet, Connor T.A. Brenna, Beverley A. Orser, Stephen Choi
Neurol Clin Pract Feb 2022, 12 (1) 76-84; DOI: 10.1212/CPJ.0000000000001132

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Article Information

vol. 12 no. 1 76-84
DOI: 
https://doi.org/10.1212/CPJ.0000000000001132

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
2163-0402
Online ISSN: 
2163-0933
History: 
  • Received April 21, 2021
  • Accepted July 23, 2021
  • First Published August 9, 2021.

Article Versions

  • Previous version (August 9, 2021 - 12:48).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2021 American Academy of Neurology

Author Disclosures

    1. Lilia Kaustov, PhD,
    2. Andrew Fleet, PhD (andrew.fleet{at}sunnybrook.ca),
    3. Connor T.A. Brenna, MD (connor.brenna{at}mail.utoronto.ca),
    4. Beverley A. Orser, MD, PhD (beverley.orser{at}utoronto.ca) and
    5. Stephen Choi, MSc, MD
  1. Lilia Kaustov, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Andrew Fleet, PhD (andrew.fleet{at}sunnybrook.ca),
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Connor T.A. Brenna, MD (connor.brenna{at}mail.utoronto.ca),
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Beverley A. Orser, MD, PhD (beverley.orser{at}utoronto.ca) and
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. I receive travel support as a member of the Board of Trustees of the International Anesthesia Research Society to attend the annual meeting and board meetings.

    Editorial Boards:
    1. NONE

    Patents:
    1. I am a named inventor of a patent entitled, Method for prevention and/or treatment of memory impairment. Patent US9517265. I am a named inventor of a patent entitled, Cell Permeable inhibitory agent and methods of use thereof in treatment of cognitive and mood disorders. US 10,981,954.

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical procedures or imaging studies:
    1. Perioperative Brain Health Centre is a research unit dedicated to improving cognition in surgical patients. This is a not-for-profit virtual research group associated with Sunnybrook HSC, Canada.

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. I am the named principal Investigator of a Canadian Institutes of Health Research Grant that provides operating support for my bench research.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Stephen Choi, MSc, MD
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. 1) CogState Ltd. - No cost access to CogState Brief Battery software for 2 ongoing clinical trials

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. 1) The Dana Foundation Clinical Neuroscience Research Grant

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. Department of Anesthesia (LK, AF, BAO, SC), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Perioperative Brain Health Centre (LK, CTAB, BAO, SC), Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine (CTAB, BAO, SC), University of Toronto, Ontario, Canada; and Department of Physiology (BAO), University of Toronto, Ontario, Canada.
  1. Correspondence
    Dr. Choi stephen.choi{at}sunnybrook.ca
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