Predictive Modeling for Clinical Features Associated With Neurofibromatosis Type 1
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Article Information
- Received August 6, 2020
- Accepted February 25, 2021
- First Published April 14, 2021.
Article Versions
- Previous version (April 14, 2021 - 14:12).
- You are viewing the most recent version of this article.
Author Disclosures
- Stephanie M. Morris, MD*,
- Aditi Gupta, PhD*,
- Seunghwan Kim, MS,
- Randi E. Foraker, PhD, MA,
- David H. Gutmann, MD, PhD and
- Philip R.O. Payne, PhD
- Stephanie M. Morris, MD*,
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Springworks Therapeutics - consultant
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1) NIH, 5K12NS00169017, trainee, 2015-2018
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- Aditi Gupta, PhD*,
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Centene Corporation contract (P19-00559) for the Washington University-Centene ARCH Personalized Medicine Initiative.
(1) NCATS, IDDRC Collaborative Innovation Award U01, Project Manager, 2020-2024 (2) NIH/NHGRI 5R01HG00935104, Researcher, 2017-2021 Stock/Stock Options, Medical Equipment & Materials: My husband has stocks in (1) Cigna (2) TherapeuticsMD (3) Ocugen, Inc.
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- Seunghwan Kim, MS,
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Centene Corporation contract (P19-00559) for the Washington University-Centene ARCH Personalized Medicine Initiative.
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- Randi E. Foraker, PhD, MA,
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Current Epidemiology Reports, Cardiovasular Disease Section Editor, 2018- present
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NIH/NCI, 1R01CA226078, MPI, 2018-2023
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Global Autoimmune Institute
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- David H. Gutmann, MD, PhD and
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Glia Neuro-Oncology
NF1 Gene, 1999. Identification of the NF1 gene and protein. mTOR, 2012. Identification of NF1 protein as mTOR regulator.
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PI, NCI, R01, Defining risk factors for NF1-optic glioma, 2016-2021 PI, NIH, Defining the mechanistic basis for neurofibromatosis-1 nervous system disease heterogeneity. 2016-2024.
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PD, The Giorgio Foundation, NF1-Dermal Neurofibroma Consortium, 2016-2021 PI, Neurofibromatosis Therapeutic Acceleration Program, Leveraging human iPSCs to determine the impact of patient-derived NF1 gene mutations on peripheral sensory neuron-driven Schwann cell growth, 2018-2021 PI, Gilbert Family Foundation, Vision Restoration Initiative, 2019-2022 PI, PLGA, Human iPSC PLGA Models for Therapeutic Drug Discovery and Evaluation, 2020-2022
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TSC knockout (GFAP-Cre) mouse (Tuberous Sclerosis Alliance)
NF1 gene patent, University of Michigan, 2000 to 2015
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- Philip R.O. Payne, PhD
(1) Geisinger Health
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(1) BMC Medical Informatics and Decision Making, Section Editor (Healthcare Information Technology, 2016-2020, (2) JAMIA Open, Associate Editor, 2018-Present
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Payne PR and Embi PJ, Editors. Translational Informatics: Realizing the Promise of Knowledge-driven Healthcare, 1st Edition. Springer. 2015.
(1) Centene Corporation contract (P19-00559) for the Washington University-Centene ARCH Personalized Medicine Initiative.
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(1) NCI, Cancer Center Support Grant, Co-I, 2020-2025, (2) NCATS, National Center for Digital Health Informatics Innovation (CD2H) U24, Site PI, 2017-2022, (3) NCATS, The Washington University Institute for Clinical and Translational Science UL1, Co-I, 2017-2022, (4) NCI, Assessing Efficacy and Implementation of an EHR Tool to Assess Heart Health Among Cancer Survivors R01, Co-I, 2018-2022, (5) NCATS, IDDRC Collaborative Innovation Award U01, Co-I, 2020-2024, (6) NCATS, Instrumenting the Delivery System for a Genomics Research Information Commons (GRIN) U01, Site PI, 2019-2024, (7) NCATS, National COVID Cohort Collaborative (N3C) Administrative Supplement, Site PI, 2020-2021
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(1) TRIAD (Translational Research Informatics and Data Management Grid), OSU Innovation Foundation
(1) TRIAD (Translational Research Informatics and Data Management Grid), OSU Innovation Foundation
(1) Signet, LLC, 2014-Present, (2) Aver, Inc, 2012-Present
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- Department of Neurology (DHG), Washington University, St. Louis, MO; and Institute for Informatics (SMM, AG, SK, REF, PROP), Washington University, St. Louis, MO.
- Correspondence
Dr. Payne prpayne{at}wustl.edu
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