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August 2021; 11 (4) Research

Cohort Study in Parkinsonism

Delayed Transit, Accelerated Gastric Emptying, and Prodromal Dysmotility

Katayoun Khoshbin, Anhar Hassan, Michael Camilleri
First published November 2, 2020, DOI: https://doi.org/10.1212/CPJ.0000000000001003
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Article Information

vol. 11 no. 4 e407-e413
DOI: 
https://doi.org/10.1212/CPJ.0000000000001003
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
2163-0402
Online ISSN: 
2163-0933
History: 
  • Received June 8, 2020
  • Accepted September 21, 2020
  • First Published November 2, 2020.

Article Versions

Copyright & Usage: 
© 2021 American Academy of Neurology

Author Disclosures

    1. Katayoun Khoshbin, MD,
    2. Anhar Hassan, MBBCh, FRACP and
    3. Michael Camilleri, MD
  1. Katayoun Khoshbin, MD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Anhar Hassan, MBBCh, FRACP and
    3. Scientific Advisory Boards:

    1. 1) DSMB for Clinical Trial Readiness for SCA1 and SCA3(U01) (no compensation)

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. (1) Parkinsonism and Related Disorders, Editorial Board Member, 2016-. No personal compensation. (2) Moving Along, Movement Disorders Society newsletter. Editorial Board Member, 2019-. No personal compensation.

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. (1) Intrabio research support

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Michael Camilleri, MD
    4. Scientific Advisory Boards:

    1. Takeda (TAK-954); Ironwood (MD-7245); Enterin (ENT-01); Dignify (spinal cord injury); Alfasigma (velusetrag); Rhythm & Allergan (relamorelin); Kallyope (obesity); EA Pharma (elobixibat); AEON Biopharma (gastroparesis); QED Therapeutics (FGFR4 for bile acid synthesis); Check-Cap (motility capsule); Arena (olorinab); Biokier (diabetes); Protagonist Therapeutics (analgesia)

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. American Journal of Physiology - GI and Liver Physiology, associate editor, 2015-present

    Patents:

    1. 1. Capsule for colonic transit by scintigraphy 2. 13C-mannitol for permeability measurement 3. obesity-metabolomics to identify different phenotypes

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. Biokier, Check-Cap, Protagonist Therapeutics, Enterin, Salix, AEON Biopharma, QED Therapeutics

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Takeda (TAK-954, gastroparesis); Allergan (eluxadoline, bile acid diarrhea); Novartis (tropifexor, bile acid diarrhea); Vanda (NK1 antagonist, tradipitant)

    Research Support, Government Entities:

    1. Principal Investigator for 3 grants from National Institutes of Health: R01-DK67071 (2007-2021); R01- DK115950 (2018-2021); R01-DK122280 (2019-2024)

    Research Support, Academic Entities:

    1. Mayo Clinic Distinguished Investigator

    Research Support, Foundations and Societies:

    1. ILSI North American (ILS-258586, studies on permeability)

    Stock/Stock Options/Board of Directors Compensation:

    1. ILSI North America (studies of permeability)

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER) (KK, MC), Division of Gastroenterology and Hepatology; and Department of Neurology (AH); Mayo Clinic, Rochester, MN.
  1. Correspondence
    Dr. Camilleri camilleri.michael{at}mayo.edu
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