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February 2021; 11 (1) Research

Equipoise in Management of Patients With Acute Symptomatic Carotid Stenosis (Hot Carotid)

Aravind Ganesh, Luca Bartolini, Ravinder-Jeet Singh, Abdulaziz S. Al-Sultan, David J.T. Campbell, John H. Wong, Bijoy K. Menon
First published February 5, 2020, DOI: https://doi.org/10.1212/CPJ.0000000000000812
Aravind Ganesh
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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Luca Bartolini
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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Ravinder-Jeet Singh
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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Abdulaziz S. Al-Sultan
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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David J.T. Campbell
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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John H. Wong
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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Bijoy K. Menon
Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
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Full PDF
Citation
Equipoise in Management of Patients With Acute Symptomatic Carotid Stenosis (Hot Carotid)
Aravind Ganesh, Luca Bartolini, Ravinder-Jeet Singh, Abdulaziz S. Al-Sultan, David J.T. Campbell, John H. Wong, Bijoy K. Menon
Neurol Clin Pract Feb 2021, 11 (1) 25-32; DOI: 10.1212/CPJ.0000000000000812

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Article Information

vol. 11 no. 1 25-32
DOI: 
https://doi.org/10.1212/CPJ.0000000000000812

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
2163-0402
Online ISSN: 
2163-0933
History: 
  • Received September 4, 2019
  • Accepted December 3, 2019
  • First Published February 5, 2020.

Article Versions

  • Previous version (February 5, 2020 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2020 American Academy of Neurology

Author Disclosures

    1. Aravind Ganesh, MD, DPhil,
    2. Luca Bartolini, MD,
    3. Ravinder-Jeet Singh, MD,
    4. Abdulaziz S. Al-Sultan, MD, FRCPC,
    5. David J.T. Campbell, MD, PhD, FRCPC,
    6. John H. Wong, MD, MSc, FRCSC and
    7. Bijoy K. Menon, MD, MSc, FRCPC
  1. Aravind Ganesh, MD, DPhil,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. (1) University of Calgary Post-Graduate Medical Education (PGME): travel funding for conferences (2) St John's College, Oxford: travel funding, honoraria (3) International Stroke Conference: Junior Investigator grants (4) American Academy of Neurology: Futures in Neurological Research award, resident scholarships

    Editorial Boards:
    1. (1) Neurology Editorial Board, Disputes and Debates, 2018- Present (2) Neurology:Clinical Practice Editorial Board, Practice Current, 2019- Present (3) Neurology Resident & Fellow Section, Editorial Board Member, 2014-2018 (4) Stroke, Editorial Board Member, 2019-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Adkins Research Group: honoraria for research consultation (2) Genome BC: honoraria for research consultation (3) MD Analytics: honoraria for research consultation (4) My Medical Panel: honoraria for research consultation

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1) The Rhodes Trust (2) Wellcome Trust

    Stock/Stock Options/Board of Directors Compensation:
    1. (1) SnapDx (2) TheRounds.ca (3) Advanced Health Analytics (AHA Health Ltd)

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Luca Bartolini, MD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Neurology Clinical Practice, Section Editor, 2015 - present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Dr. Bartolini reports having received research support from the NINDS Division of Intramural Research.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Dr. Bartolini reports receiving grant support from the American Epilepsy Society / Epilepsy Foundation of America

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Ravinder-Jeet Singh, MD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical procedures or imaging studies:
    1. Clinical procedure/imaging study: 90%

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Abdulaziz S. Al-Sultan, MD, FRCPC,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. David J.T. Campbell, MD, PhD, FRCPC,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Diabetes Canada, Travel award

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Alberta Innovates, Clinician-Fellow, 2013-2019

    Research Support, Academic Entities:
    1. O'Brien Institute for Public Health

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. John H. Wong, MD, MSc, FRCSC and
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. Vascular stent Stock/Stock Options, Medical Equipment & Materials: Fluid Biotech Inc., 2013-present

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Bijoy K. Menon, MD, MSc, FRCPC
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Commercial entity. Travel honoraria from Penumbra Inc.

    Editorial Boards:
    1. Editorial Board, Stroke

    Patents:
    1. A provisional patent 62/086077 for triaging systems in ischemic stroke

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. Dr. Menon BK reports membership of the Steering and Executive Committee, ESCAPE trial that received support from Covidien Inc., Site Principal Investigator, SOCRATES Trial, sponsored by Astra Zeneca.

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Research funding from 1) Canadian Institute of Health Research, 2) Heart and Stroke Foundation of Canada, 3) Alberta Innovates Health Solutions, 4) Hotchkiss Brain Institute and the 5) Faculty of Medicine, University of Calgary

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. Department of Clinical Neurosciences (AG, R-JS, ASA-S, JHW, BKM), University of Calgary, Canada; Clinical Epilepsy Section (LB), National Institutes of Health, Bethesda, MD; Centre for Urban Health Solutions (DJTC), St. Michael's Hospital, Toronto, Canada; and Department of Medicine (DJTC), Department of Community Health Sciences (DJTC, BKM), Department of Radiology (JHW, BKM), and The Hotchkiss Brain Institute (JHW, BKM), University of Calgary, Canada.
  1. Correspondence
    Dr. Menon docbijoymenon{at}gmail.com
View Full Text

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