Technology-enabled assessments to enhance multiple sclerosis clinical care and research
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Article Information
- Received March 13, 2019
- Accepted June 19, 2019
- First Published September 6, 2019.
Article Versions
- Previous version (September 6, 2019 - 12:45).
- You are viewing the most recent version of this article.
Author Disclosures
- Gabrielle Macaron, MD,
- Brandon P. Moss, MD,
- Hong Li,
- Laura E. Baldassari, MD,
- Stephen M. Rao, PhD,
- David Schindler, BS,
- Jay L. Alberts, PhD,
- Malory Weber,
- Malissa Ayers, PA-C,
- François Bethoux, MD,
- Adrienne Boissy, MD,
- Desiree Chizmadia, CNP,
- Devon S. Conway, MD,
- Charlene Fink, CNS-BC,
- Robert J. Fox, MD,
- Shauna Gales, PA-C,
- Bethany Green, CNP,
- Claire Hara-Cleaver, CNP,
- Neal Jordan,
- Kedar R. Mahajan, PhD,
- Marisa P. McGinley, DO,
- Deborah M. Miller, PhD,
- Marie Namey, CNS-BC,
- Alexander Rae-Grant, MD,
- Mary Rensel, MD,
- Hilary Young, PA-C,
- Mary A. Willis, MD,
- Daniel Ontaneda, MD,
- Jeffrey A. Cohen, MD and
- Robert A. Bermel, MD
- Gabrielle Macaron, MD,
Scientific Advisory board for Genentech
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
I have received fellowship funding from Biogen (Biogen Fellowship Grant 6873-P-FEL) from November 2017 to October 2018.
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I am currently receiving fellowship funding from the National Multiple Sclerosis Society (National Multiple Sclerosis Society Institutional Clinician Training Award ICT 0002) since November 2018.
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- Brandon P. Moss, MD,
(1) Genentech
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(1) Sanofi Genzyme
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(1) Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen. Stock/Stock Options, Medical Equipment & Materials: (1) Pfizer, 1 year
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- Hong Li,
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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- Laura E. Baldassari, MD,
(1) Teva
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(1) Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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(1) National Multiple Sclerosis Society (Grant FP-1606- 24540)
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- Stephen M. Rao, PhD,
Data safety monitoring board, University of Florida
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Editor-in-Chief, Journal of the International Neuropsychological Society Associate Editor, American Psychologist
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Received consulting fees from University of Florida.
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
Biogen
NIH
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Qr8 Health, Inc.
Cleveland Clinic
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- David Schindler, BS,
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Various patents related to the MSPT and contained assessment modules.
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Qr8 Health, Director of Product Development, 2 years
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen. Stock/Stock Options, Medical Equipment & Materials: Qr8 Health, 2 years
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- Jay L. Alberts, PhD,
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Troop Readiness Evaluation with Augmented Reality Return-to-Duty (READY) System NIPA: Non-Invasive Intracranial Pressure Assessment AR/VR in Neurological Care Smart Phone Enabled Assessment of Timed Up and Go Test Gait and Balance Smart Footwear
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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- Malory Weber,
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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- Malissa Ayers, PA-C,
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(1)Genzyme, honoraria (2)Biogen, honoraria (3)Novartis, honoraria
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(1)Genzyme (2)Biogen (3) Novartis
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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- François Bethoux, MD,
(1) Ipsen. (2) GW Pharma
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(1) TeamWorks
(1) International Journal of MS Care, editorial board member, 2008-present. (2) US Neurology, Multiple Sclerosis section editor, 2010-present.
(1) Multiple Sclerosis Performance Test
(1) Multiple Sclerosis and Related Disorders: Diagnosis, Medical Management, and Rehabilitation, Demos Publishing, 2013. (2) Multiple Sclerosis and Related Disorders: Diagnosis, Medical Management, and Rehabilitation. 2nd edition, Demos Publishing, 2018
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(1) Abide Pharmaceuticals. (2) MedRhythms
(1) Biogen
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1) Biogen. (2) Adamas Pharmaceuticals. (3) Acorda Therapeutics
(1)NIH - 1UH3NS100543-01, co-investigator, 2016-2021
1) Cleveland Clinic Foundation
(1) Patient-Centered Outcomes Research Institute. (2) Consortium of MS Centers. (3) National Multiple Sclerosis Society
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Multiple Sclerosis Performance Test, Biogen
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- Adrienne Boissy, MD,
Immediate family member on: (1) Blockade Medical (2) Codman Neurovascular (3) Medtronic (4) Stryker (5) Teladoc (6) Nervive (7) Perflow Ltd
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(1) Journal of Patient Experience 2015-2019
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(1)An immediate family member received publishing royalties from Endovascular Tachniques in the Management of Cerebrovascular Disease, Informa Healthcare 2008. (2) Communication the Cleveland clinic Way, McGraw Hill
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An immediate family member has consulted for: 1)Possis 2)Cohen Group 3)MedyMatch
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 health and Biogen
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Immediate family member and self : (1) Blockade Medical Immediate Family Member: (1) Cordinus Vascular Robotics
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Immediate family member: Medhana MEdical LLC Stock/Stock Options, Medical Equipment & Materials: Dr Boissy and an immediate family member: (1) EV3, 2009 (2)Chestnut Medical Technologies, 2009 (3) Neurvana
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- Desiree Chizmadia, CNP,
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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- Devon S. Conway, MD,
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I have served as a consultant for Novartis Pharmaceuticals and Tanabe Laboratories.
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(1) Novartis Pharmaceuticals
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(1) National Multiple Sclerosis Society
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- Charlene Fink, CNS-BC,
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did patient speaker engagements for Teva Pharmaceuticals and Sanofi Genzyme
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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- Robert J. Fox, MD,
Actelion, Biogen Idec, Immunic, Novartis
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Editorial Board, Neurology Editorial Board, Multiple Sclerosis Journal
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Multiple Sclerosis and Related Disorders, Demos Medical, 2019
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Actelion, Biogen, EMD Serono, Genentech, Novartis, Teva
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
Research grants from Novartis and Biogen
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National MS Society, RG 4778-A-6, 2013-2019; NIH 1U01NS082329-01A1, 2013-2019; Consortium of MS Centers
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- Shauna Gales, PA-C,
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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- Bethany Green, CNP,
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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- Claire Hara-Cleaver, CNP,
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Commercial Advisor for Novartis, Genentech and Biogen
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I currently work for Biogen, the paper was submitted while I was still employed by Cleveland Clinic Mellon Center as a Nurse Practitioner
Advisor for Novartis, Genentech, Biogen
Advisor for Novartis, Genentech, Biogen
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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- Neal Jordan,
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Epic Systems Corporation, Consultant, 12 years
IT Consultant for the Cleveland Clinic, IT Consultant for Epic Systems Corporation
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Epic Systems Corporation
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- Kedar R. Mahajan, PhD,
Dr. Mahajan served on a scientific advisory board for Sanofi Genzyme and Genentech.
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Dr. Mahajan received personal fees for an unbranded round table discussion with Sanofi Genzyme.
Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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Dr. Mahajan has received research support from NMSS-ABF (FAN- 1507-05605) and NIH/NINDS (1K23NS109328).
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- Marisa P. McGinley, DO,
1) Genentech 2) Genzyme
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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1) National Multiple Sclerosis Society
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- Deborah M. Miller, PhD,
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Associate Editor for Quality of Life Research (2009 - 2011) Associate Editor for Journal of Rehabilitation Research and Development (2009 - 2011)
Deborah Miller shares rights to intellectual property underlying the Multiple Sclerosis Performance Test, currently licensed to Qr8 Health and Biogen
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Consultant to Can Do MS (2009 - 2019)
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Invited speaker for the Consortium of Multiple Sclerosis Centers.
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- Marie Namey, CNS-BC,
(1) Biogen, (2) Sanofi Genzyme, (3) Genentech, (4) Celgene
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(1) Biogen, (2) Sanofi Genzyme, (3) Genentech
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
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- Alexander Rae-Grant, MD,
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Neurology, Evidence Review Team, 2011-2018
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Handbook of Multiple Sclerosis, Springer Healthcare, 2010 Comprehensive review of clinical neurology, Wolters Kluwer, 2012. 5 minute consult in neurology, Wolters Klower, 2012 Comprehensive review of clinical neurology second edition, LWW, 2016. Ultimate review of neurology DEMOS 2016 Multiple Sclerosis and Related disorders, DEMOS, 2014
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I am neurology editor for DynaMed an online point of care evidence based tool for clinicians. This is a 50% time commitment. There is no pharma funding (all subscription services) and not related to this paper.
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- Mary Rensel, MD,
1. Serono
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Biogen, Honoraria for speaking engagements Novartis, Honoraria for speaking engagements Teva, Honoraria for speaking engagements Genzyme, Honoraria for speaking engagements
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Biogen, Honoraria for speaking engagements Novartis, Honoraria for speaking engagements Teva, Honoraria for speaking engagements Genzyme, Honoraria for speaking engagements, Celgene- advisory board
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen
Medimmune Genzyme,educational grant
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National Multiple Sclerosis Society
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- Hilary Young, PA-C,
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Cleveland Clinic shares rights to intellectual property contained within the MSPT, currently licensed to Qr8 Health and Biogen.
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- Mary A. Willis, MD,
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International Journal of MS Care, member of editorial board, 7 years
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Genzyme, Biogen, Novartis, Ipsen
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- Daniel Ontaneda, MD,
1) Genzyme, 2) Genentech, 3) Biogen Idec, 4)Novartis
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Biogen Idec, Genzyme, Genentech, Merck, Novartis
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1) Genzyme, 2) Novartis, 3) Genentech
NIH R35NS097303 Co-investigator 2017-2018
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NMSS PCORI Race to Erase Foundation
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- Jeffrey A. Cohen, MD and
Alkermes 4/9/18 - Consulting Biogen 6/4/18 - Consulting Convelo 2/28/18, 3/1/18, 4/2/18, 4/27/18, 5/31/18, 6/28/18, 7/31/18, 8/28/18, 10/2/18, 10/30/18, 11/28/18, 12/24/18, 1/29/19, 2/26/19, 3/26/19 - Consulting EMD Serono 12/13/17, 6/28/18 - Consulting ERT 5/9/18 - Consulting Gossamer Bio 6/27/18 - Consulting Novartis 6/27/17, 1/27/18, 4/23/18, 4/24/18 - Consulting ProValuate 6/11/18 - consulting
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Mylan 10/26/17, 5/17/18 - speaker honorarium Synthon 4/5/18 - speaker honorarium
2019-present - Co-Editor Multiple Sclerosis Journal
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- Robert A. Bermel, MD
Biogen, Genentech, Genzyme, Novartis
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Biogen, Genzyme, Genentech, Novartis, Roche
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Cleveland Clinic shares rights to intellectual property underlying the MSPT, currently licensed to Qr8 Health and Biogen.
Novartis, Genentech, Biogen
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Robert Bermel shares rights to intellectual property underlying the MSPT, currently licensed to Qr8 Health and Biogen
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- Mellen Center for Multiple Sclerosis (GM, BPM, LEB, MW, MA, FB, AB, DC, DSC, CF, RJF, SG, BG, CH-C, KRM, MPM, DMM, MN, AR-G, MR, HY, MAW, DO, JAC, RAB), Neurological Institute, Cleveland Clinic Foundation; Department of Quantitative Health Sciences (HL), Cleveland Clinic; Schey Center for Cognitive Neuroimaging (SMR), Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic Foundation; Department of Biomedical Engineering (DS, JLA), Lerner Research Institute, Cleveland Clinic Foundation, OH; and Epic Systems Corporation (NJ), Verona, WI.
- Correspondence
Dr. Bermel bermelr{at}ccf.org
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