Small fiber neuropathy presenting during the antecedent period of undifferentiated arthritis prior to rheumatoid arthritis
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In contrast to Sjögren syndrome (SS),1 small fiber neuropathies (SFN) associated with rheumatoid arthritis (RA) have been sparsely reported.2 Furthermore, many patients with RA pass through an antecedent period termed undifferentiated arthritis (UA),3 in which they may experience an inflammatory arthritis not satisfying criteria for RA or another inflammatory syndrome. SFN may be a rare complication occurring during this presaging period of UA. Yet this possibility is relevant, given that SFN may antedate systemic manifestations of other rheumatic diseases (i.e., SS).1 We report an unusual case of SFN initially developing in a patient with UA, who ultimately develops RA.
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- Received April 28, 2017.
- Accepted July 19, 2017.
- © 2017 American Academy of Neurology
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